BMS 986158
CAS No. 1800340-40-2
BMS 986158 ( BMS986158 )
产品货号. M12735 CAS No. 1800340-40-2
BMS-986158 (BMS986158) is a potent and selective BET inhibitor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2203 | 有现货 |
|
10MG | ¥3969 | 有现货 |
|
25MG | ¥6359 | 有现货 |
|
50MG | ¥8748 | 有现货 |
|
100MG | ¥11826 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称BMS 986158
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述BMS-986158 (BMS986158) is a potent and selective BET inhibitor.
-
产品描述BMS-986158 (BMS986158) is a potent and selective BET inhibitor, disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth.Solid Tumors Phase 2 Clinical
-
同义词BMS986158
-
通路Chromatin/Epigenetic
-
靶点Bromodomain
-
受体Bromodomain
-
研究领域Cancer
-
适应症Solid Tumors
化学信息
-
CAS Number1800340-40-2
-
分子量495.63
-
分子式C30H33N5O2
-
纯度>98% (HPLC)
-
溶解度DMSO : 1 mg/mL 2.02 mM
-
SMILESOC(C)(C)C1=CC=C2C(N([C@H](C3=CC=CC=C3)C4CCOCC4)C5=C2N=CC(C6=C(C)N=NN6C)=C5)=C1
-
化学全称(S)-2-(3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-(phenyl(tetrahydro-2H-pyran-4-yl)methyl)-5H-pyrido[3,2-b]indol-7-yl)propan-2-ol
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册
关联产品
-
JQ1-Az
JQ1-Az is a JQ1 derivative.
-
GNE-049
GNE-049 (GNE049) is a potent, selective, orally available inhibitor of CBP/p300 bromodomain with biochemical IC50 of 1.1/2.3 nM, respectively.
-
GNE-272
A potent and selective the bromodomains of CBP/EP300 inhibitor with IC50 of 0.02 and 0.03 uM for CBP and EP300, respectively.